Before
AfterNeurotoxins
Soften expression lines while preserving natural movement.
Feel Better.Look Better.Live Better.
Medically guided aesthetics and root-cause wellness in Midtown Manhattan, New York.Medically guided aesthetics, longevity and root-cause wellness — thoughtfully tailored to you by founder-providers in Midtown Manhattan, New York.
The Caleyo Approach
A boutique destination for regenerative aesthetics, longevity and personalized wellness — where clinical expertise meets an unhurried, deeply personal experience.
- Years of clinical experience
- 13+
- Founder-providers, one plan
- 2
- Care in English & Spanish
- EN · ES
01 — Look Your Best
Aesthetics
Neurotoxins · Dermal Fillers · Facial Balancing · Biostimulators · Microneedling · Skin Rejuvenation · PRP / PRF · Hair Restoration
Explore Aesthetics
02 — Feel & Live Your Best
Longevity & Wellness
Functional & Root-Cause Medicine · Hormone Optimization · Medical Weight Optimization · Peptide Therapy · IV & NAD+ · Metabolic Health · Preventive Wellness
Explore Longevity & WellnessAesthetics
The Art ofNatural Refinement.
Every aesthetic plan begins with your anatomy, your goals and an artist’s eye. Our approach is subtle, regenerative and individual — refreshed, never overdone.
View All Aesthetic Treatments
01
Neurotoxins
Soften expression lines while preserving natural movement and expression.
Discover
02
Dermal Fillers
Restore volume and contour with a soft, balanced, natural finish.
Discover
03
Facial Balancing
Subtle, individualized refinement that enhances facial harmony.
Discover
04
Biostimulators
Stimulate your own collagen for gradual, long-lasting renewal.
Discover
05
Microneedling & Skin Rejuvenation
Refine tone, texture and radiance for healthier-looking skin.
Discover
Results that look like you — refreshed, confident and never overdone.
The Caleyo Standard
Longevity & Wellness
Feel like yourself again —from the root cause up.
- 01Functional and root-cause medicineLook beyond symptoms to what is really driving how you feel.
- 02Hormone OptimizationRestore energy, mood, sleep and vitality with personalized care.
- 03Medical Weight LossMedically guided, sustainable progress — led by an NP and dietitian.
- 04Peptide TherapyConsidered for recovery, metabolism and healthy aging when it fits the plan.
- 05IV & NAD+ TherapyCellular support for energy, clarity and recovery.
- 06Nutrition and metabolic healthLabs, nutrition and lifestyle strategies for long-term health.
- 07Longevity MedicineEvidence-informed longevity care for strength, metabolism and function.
Patient Results
Results That Speakfor Themselves.
Subtle, individualized outcomes designed around your goals, features and wellbeing.
BeforeAfter
Before
AfterLip Enhancement
Natural volume and balance with a soft, elegant finish.
Before
AfterGolden Eye (PRF + EZ Gel)
Brighter, refreshed under-eyes with improved skin quality.
Before
AfterFacial Balancing
Subtle contouring that enhances overall facial harmony.
Before
AfterSkin Rejuvenation
Improved tone, texture and radiance.
Before
AfterHair Restoration
Fuller-looking hair through a regenerative approach.
Results are individual. Every treatment plan is customized to each patient’s anatomy, goals and clinical assessment.
Meet the founders
Two founders. One practice.
Emmanuel Pelayo and Jaime Calderon built Caleyo Wellness so medical care and aesthetics could be planned together. Both are bilingual in English and Spanish.
MSN, NP-C, RDN · Co-founder and medical provider
Emmanuel Pelayo
Emmanuel Pelayo, MSN, NP-C, RDN is co-founder and medical provider. He is an adult medicine nurse practitioner and a registered dietitian, with more than 13 years of clinical experience. Care is available in English and Spanish.
- Adult medicine
- Nutrition
- Metabolic and hormone health
- English & Spanish
Co-founder and aesthetic provider
Jaime Calderon
Jaime Calderon is co-founder and aesthetic provider. He partners with Emmanuel on plans that respect natural features and the person in front of him. Care is available in English and Spanish.
- Aesthetic planning
- Natural-looking results
- Regenerative skin care
- English & Spanish
Meet Your Providers
Care Starts Witha Conversation.
Two founder-providers, one connected plan. Medical, nutritional and aesthetic expertise under one roof — so you never have to piece your care together yourself.
Book Your ConsultationMSN, NP-C, RDN
Co-founder · Medical provider
Emmanuel Pelayo
Adult medicine nurse practitioner and registered dietitian with more than 13 years of clinical experience. Emmanuel’s approach to functional medicine, hormones and weight care is bilingual — English and Spanish.
- Adult medicine
- Nutrition
- Hormone health
- Weight care
Aesthetic provider
Co-founder · Aesthetic provider
Jaime Calderon
Jaime leads aesthetic care with a preference for natural-looking results and unhurried planning. He is bilingual in English and Spanish.
- Neurotoxins
- Dermal Fillers
- Facial Balancing
- PRP
★★★★★
5.0 on Google · 30 reviews
Care Remembered LongAfter the Appointment.
★★★★★
“I have been coming to Caleyo Wellness for my aesthetic treatments for quite some time, and I am so happy with my results. What I appreciate most is the time and attention they take to really listen to my concerns and explain every treatment before doing anything.…”
★★★★★
“I have been coming to Caleyo Wellness for both aesthetics and overall wellness, and I am so happy with my experience and results. Over time, I have had treatments including Radiesse, Daxxify, microneedling with a vampire facial, and Autocorre, a natural filler made using my own PRF and plasma. I also use the medical-grade skincare products they recommended for me.…”
★★★★★
“Wonderful experience with Emmanuel Pelayo! I really appreciated the personalized and thoughtful approach to weight loss with GLP-1 treatment. Everything was clearly explained, and I felt heard, supported, and never judged. Knowledgeable, caring, and focused on healthy, realistic results. Highly recommend!”
★★★★★
“I truly cannot say enough amazing things about Caleyo Wellness! If I could give them 10 stars, I absolutely would. From the moment you walk into the clinic, you feel welcomed. The space is beautiful, clean, relaxing, and has such a positive, calming atmosphere. Everyone is friendly, professional, and genuinely makes you feel like you're in the best hands.…”
★★★★★
“From the moment I got to the practice, they were very sweet and tried to understand my needs and my skin concerns. I’ve been travelling for the past three weeks and my face was so swollen, and with the rosacea I wasn’t feeling good. They suggested the Goddess STEAM Facial, and the results were incredible!…”
Your Consultation
Three Considered Steps.
- 01
Share Your Goals
Tell us what you’d like to feel, see or understand — no need to know the treatment.
- 02
Meet Your Provider
An unhurried visit that reviews your concerns, history and goals.
- 03
Leave With Clarity
A personalized plan, transparent options and absolutely no pressure.
Begin Here
Let's Start With You.
Whether you’re exploring aesthetics, hormones, weight or longevity, your journey begins with one personalized conversation.
A personal consultation · A clear plan · No pressure
We are in Midtown Manhattan at 120 East 56th Street, Suite 920, New York, NY 10022, a short walk from the Lexington Ave/59th St and 53rd St subway stations.
The right service depends on your individual concerns, health history, and goals. During a consultation, our team will take the time to understand what you're looking to achieve, explain suitable options, and help you determine the most appropriate next steps for your needs.
Yes. Our co-founders bring medical, nutritional, and aesthetic expertise together under one roof, so you can book a wellness consultation, an aesthetic consultation, or discuss both in a single plan.
Yes. Both of our co-founders are bilingual, and we are happy to provide your consultation and care in English or Spanish.
Functional medicine looks beyond symptoms to understand what may be driving them, considering your health history, lifestyle, nutrition, hormones, and metabolic health, so your plan addresses the bigger picture.
Send a message
At Caleyo Wellness, we guide you toward health, beauty, and well-being. Questions about services, pricing, or booking are welcome.
- Visit us — Expert-led care in a calm Midtown studio.
- Call or text — The team can answer a quick question — (212) 547-9462
- Email us ([email protected]) or use the form belowbeside this note — for services, programs, memberships, or collaborations.
- Book online
We look forward to helping you feel, look, and live better.
Visit120 East 56th Street, Suite 920
New York, NY 10022Phone
(212) 547-9462Email
[email protected]HoursMonday 6:00 PM – 8:00 PMTuesday 6:00 PM – 8:00 PMWednesday 6:00 PM – 9:00 PMThursday ClosedFriday 10:00 AM – 6:00 PMSaturday 10:00 AM – 6:00 PMSunday Closed
Required fields inside the form are marked with an asterisk. They include your name, email, phone, and the treatment you are asking about.
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